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Andalusia is a historic neighborhood and unincorporated community in Bensalem Township, Pennsylvania, United States. It borders Philadelphia along the Poquessing Creek. The area is the southernmost part of the township and of the county. Its boundaries are Woodhaven Road to the northeast, the Delaware River to the east and south, and Poquessing Creek to the north and west. Interstate 95 - Delaware Expressway runs through its southeastern section near the Delaware River. The neighborhood takes its name from Andalusia, the estate of Philadelphia financier Nicholas Biddle (1786–1844), now preserved as a National Historic Landmark.