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Calpella is an unincorporated community and census-designated place (CDP) in Mendocino County, California, United States. It is located on the Russian River, 6 miles (10 km) north of Ukiah. It is situated within the Ukiah Valley, at the intersection of U.S. Route 101 and State Route 20. The population was 799 at the 2020 census, up from 679 in 2010. The small town is the site of the Mendocino Redwood Company mill and offices, which controls ten percent of the private land in the county.