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Casa Grande is a city in Pinal County, approximately halfway between Phoenix and Tucson, in the U.S. state of Arizona. The population was 53,658 at the 2020 census, and was estimated to be 68,927 in 2024. It is named after the Casa Grande Ruins National Monument which is actually located in Coolidge. Casa Grande is Spanish for "big house". Among resident English speakers, there is no consensus on how to pronounce the city's name. As of 2025 the population of Casa Grande is 70,156.