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Commerce is a city located in southeast Los Angeles County, California, United States. The population was 12,378 at the 2020 census, down from 12,823 at the 2010 census. It is usually referred to as the City of Commerce to distinguish it from the common noun. It is bordered by Vernon on the west, Los Angeles on the northwest, East Los Angeles on the north, Montebello on the east, Downey and Bell Gardens on the south, and Maywood on the southwest. The Los Angeles River forms part of its southwestern boundary, and the Rio Hondo separates it from Downey. Commerce is served by the Long Beach and Santa Ana freeways, as well as the Metrolink commuter rail service at the Commerce station.