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Greeleyville is a town in Williamsburg County, South Carolina, United States. The population was 438 at the 2010 census. The town was originally chartered on December 20, 1893. Greeleyville's seal and flag feature a depiction of the first Town Hall, which was built in the 1890s, as well as two arms, one black and one white, holding a tobacco leaf and a cotton boll. These symbols represent the unity and cooperation among all the people of Greeleyville and pay tribute to the town's agricultural heritage.