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Joplin is a city in Jasper and Newton counties in the U.S. state of Missouri. Most of the city lies in Jasper County, with the southern portion extending into Newton County. With a population of 51,762 at the 2020 census, Joplin is the 12th most-populous city in the state. The city covers an area of 38.21 square miles (99.0 km2) on the outer edge of the Ozark Mountains in southwestern Missouri. Joplin is the principal city of the three-county Joplin metropolitan area, which is home to 210,077 people and is the fifth-largest metropolitan area in Missouri. In May 2011, a violent EF5 tornado killed more than 150 people and destroyed one-third of the city.