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Lisbon is a census-designated place located in western Howard County in the state of Maryland, United States, located roughly between Baltimore and Frederick and north of Washington, D.C. It is contained in an area of roughly one square mile. Lisbon is located along Interstate 70 and Maryland Route 144 and is home to the first roundabout in Maryland. It first appeared as a CDP in the 2020 Census with a population of 282.