Medanales is an unincorporated community located in Rio Arriba County, New Mexico, United States. As of the 2020 census, Medanales had a population of 224. The community is located on the Chama River near U.S. Route 84, 14 miles (23 km) north-northwest of Española. Medanales has a post office with ZIP code 87548, which opened on March 10, 1945.