Melville is a town in St. Landry Parish, Louisiana, United States. As of the 2020 census, Melville had a population of 759. It is part of the Opelousas−Eunice Micropolitan Statistical Area. It was founded in 1889 and is known as the Atchafalaya River Catfish Capital of Louisiana. It is directly across the river from the ghost town Red Cross, Louisiana.