New Pine Creek is a census-designated place and unincorporated community in Lake County, Oregon, United States. It is Oregon's southernmost community. As of the 2020 census, New Pine Creek had a population of 111. It has a post office with a ZIP code 97635. New Pine Creek lies on U.S. Route 395 at the Oregon–California border, just north of New Pine Creek, California, and east of Goose Lake.