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Patricksburg is an unincorporated community in eastern Marion Township, Owen County, in the U.S. state of Indiana. It lies along State Road 246, west of the city of Spencer, the county seat of Owen County. Its elevation is 715 feet (218 m), and it is located at 39°18′56″N 86°57′33″W. Although Patricksburg is unincorporated, it has a post office, with the ZIP code of 47455.