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Pioche is an unincorporated town in Lincoln County, Nevada, United States, approximately 180 miles (290 km) northeast of Las Vegas. U.S. Route 93 is the main route to Pioche and bypasses the town center just to the east, with Nevada State Route 321 and Nevada State Route 322 providing direct access. Pioche is the county seat of Lincoln County. Pioche is named after François Louis Alfred Pioche, a San Francisco financier and land speculator originally from France. The town's population was 1,002 at the 2010 census.