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Salem is a city in Columbiana County, Ohio, United States. The population was 11,915 at the 2020 census. Salem was founded by Quakers in 1806 and served as a center of abolitionist activity and a station on the Underground Railroad. Originally an industrial town, Salem functions primarily as a residential community and regional commercial center. The city is home to Allegheny Wesleyan College and Kent State University at Salem. It is the principal city of the Salem micropolitan area, which comprises Columbiana County; a small portion of the city extends into Mahoning County.