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Salyer is an unincorporated community and census-designated place (CDP) in Trinity County, California, United States. Salyer is located on State Highway 299, 52 miles (84 km) east of Eureka and 93 miles (150 km) west of Redding. Its population is 389 as of the 2020 census. For statistical purposes, the United States Census Bureau has defined Salyer as a census-designated place (CDP). The census definition of the area may not precisely correspond to local understanding of the area with the same name.