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St. Matthews is a city in Jefferson County, Kentucky, United States. It forms part of the Louisville Metro government but is separately incorporated as a home rule-class city. As of the 2020 census, St. Matthews had a population of 17,534. It is the 23rd-largest city in the state. St. Matthews is one of the state's major shopping areas, home to the fifth-largest mall in Kentucky along with many smaller shopping centers along Shelbyville Road.