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Symsonia is an unincorporated community and census-designated place (CDP) in Graves County, Kentucky, United States. The community lies in the far northeastern part of the county, 13 miles (21 km) southeast of Paducah, 11 miles (18 km) northwest of Benton, and 15 miles (24 km) northeast of the county seat Mayfield, in the Jackson Purchase region of the state. As of the 2020 census, Symsonia had a population of 622.