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Wilson is a city in and the county seat of Wilson County, North Carolina, United States. It is the 23rd most populous city in North Carolina. Located approximately 40 mi (64 km) east of the capital city of Raleigh, it is served by the interchange of Interstate 95 and U.S. Route 264. As of the 2020 census, Wilson had a population of 47,851. It is also an anchor city of the Rocky Mount-Wilson-Roanoke Rapids CSA, with a total population of 297,726 as of 2018.